Pattern Logo
HomeProjectsTeamWork with usBroad Institute

Exploring multi-dimensional drug response data with axis-aligned heatmaps

In this project, we aligned drug dosage heatmaps with knockout and subtype annotations to explore whether dose level sensitivity reveals meaningful biological patterns in cell lines. While the area under the curve (AUC) provides a single summary value, mid-range doses may better capture variation in sensitivity. Subtype annotations are shown for context. Users can reorder rows and columns, zoom, and filter to explore the heatmaps.

Aligned heatmaps of drug response across cell lines.

Screenshots

  • Exploring multi-dimensional drug response data with axis-aligned heatmaps screenshot 2
  • Exploring multi-dimensional drug response data with axis-aligned heatmaps screenshot 3
  • Exploring multi-dimensional drug response data with axis-aligned heatmaps screenshot 4

Contact

We collaborate with Broad teams to explore new visualization ideas and build prototypes.

Have a visualization idea or project in mind? Email us at: pattern@broadinstitute.org.

Broad Institute Logo

© 2026 Broad Institute. All rights reserved.